How to cite this article:
Chaiyasit K, Wiwanitkit V. Change of platelet count after receiving of garlic supplementation: An observation in cancerous patient. Ann Trop Med Public Health 2013;6:378 |
How to cite this URL:
Chaiyasit K, Wiwanitkit V. Change of platelet count after receiving of garlic supplementation: An observation in cancerous patient. Ann Trop Med Public Health [serial online] 2013 [cited 2020 Sep 23];6:378. Available from: https://www.atmph.org/text.asp?2013/6/3/378/121016 |
Dear Sir,
The garlic supplementation is mentioned for its usefulness in many medical disorders including to cardiovascular diseases and malignancies. [1] Focusing on the effect of garlic supplementation on platelet, it is reported for increasing platelet count in animal models. [2] On the other hand, the ajoene in garlic is mentioned for its opposite activity, antithrombotic activity. [3] The effect on a human is still controversial, and if it was used in human cases, the careful consideration is required. Here, the authors report the observed platelet count in a lung cancer patient after lobectomy for 3 years, without any other cancer therapy, who have garlic supplementation. The data of platelet count in this case before and after the garlic supplementation therapy is shown in [Table 1]. Here, the effect of garlic supplementation on platelet count can be seen. A significant reduction of platelet count can be seen, and this confirms the nature of antithrombotic activity. This can be useful in cancerous patient who has the trend to develop thrombosis.
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Table 1: Platelet count of the patient
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| 1. |
Butt MS, Sultan MT, Butt MS, Iqbal J. Garlic: Nature’s protection against physiological threats. Crit Rev Food Sci Nutr 2009;49:538-51. |
| 2. |
Koga H, Tokunaga Y, Hisamoto T, Sujaku K, Mitsuyama K, Matsuo K, et al. Ratio of serum vascular endothelial growth factor to platelet count correlates with disease activity in a patient with POEMS syndrome. Eur J Intern Med 2002;13:70-74. |
| 3. |
Mousa SA. Antithrombotic effects of naturally derived products on coagulation and platelet function. Methods Mol Biol 2010;663:229-40. |
Source of Support: None, Conflict of Interest: None
DOI: 10.4103/1755-6783.121016
[Table 1] |
