| How to cite this article: Yasri S, Wiwanitkit V. Adverse effect after DT vaccine in adults: Observation in 1,563 cases. Ann Trop Med Public Health 2015;8:222 |
| How to cite this URL: Yasri S, Wiwanitkit V. Adverse effect after DT vaccine in adults: Observation in 1,563 cases. Ann Trop Med Public Health [serial online] 2015 [cited 2021 Apr 14];8:222. Available from: https://www.atmph.org/text.asp?2015/8/5/222/159840 |
Dear Sir,
In 2015, the promotion of diphtheria and tetanus toxoids (DT) vaccine for adults to correspond to the new emerging diphtheria in Thailand has been set. In general, the vaccine is usually given to the pediatric population as part of the national vaccine program. Focusing on giving DT vaccine to adults, it is interesting to have the clinical data on its effectiveness and safety. Here, the authors report the adverse effects of DT vaccine in adults in the vaccination program. An observation in 1,563 cases who got the vaccine during March 2015 in a medical center is analyzed. The record of the possible adverse effects due to DT vaccine is analyzed. Based on the record, there are only two incidences (0.13%). All the incidences present high fever within 3 days of vaccination. All the cases can be relieved by oral administration of acetaminophen without any complication. In fact, fever is a common problem after diphtheria, tetanus, and pertussis (DTP) and DT vaccinations in children. [1] The problem is less common in DT vaccination. [1],[2],[3] Also, the problem is usually seen in booster dosage. [2] In adults, there is limited report on this topic, and this report presents good basic epidemiological data.
| References |
| 1. |
Pollock TM, Miller E, Mortimer JY, Smith G. Post-vaccination symptoms following DTP and DT vaccination. Dev Biol Stand 1985;61:407-10.
|
| 2. |
Pollock TM, Miller E, Mortimer JY, Smith G. Symptoms after primary immunisation with DTP and with DT vaccine. Lancet 1984;2:146-9.
|
| 3. |
Feery BJ. Incidence and type of reactions to triple antigen (DTP) and DT (CDT) vaccines. Med J Aust 1982;2:511-5.
|
Source of Support: None, Conflict of Interest: None
| Check |
DOI: 10.4103/1755-6783.159840
