How to cite this article: Yasri S, Wiwanitkit V. Dengue immunoglobulin test result among cases with clinical diagnosis of dengue: A retrospective study on 115 cases. Ann Trop Med Public Health 2016;9:206-7 |
How to cite this URL: Yasri S, Wiwanitkit V. Dengue immunoglobulin test result among cases with clinical diagnosis of dengue: A retrospective study on 115 cases. Ann Trop Med Public Health [serial online] 2016 [cited 2020 Sep 21];9:206-7. Available from: https://www.atmph.org/text.asp?2016/9/3/206/179111 |
Dear Sir,
Dengue is a common tropical mosquito-borne infection with a very high endemicity in Southeast Asia. The diagnosis of the disease is widely done by clinical observation of acute febrile illness accompanied with dengue triads from complete blood count (hemoconcentration, atypical lymphocytosis, and thrombocytopenia).[1] For definitive diagnosis, either immunological test or polymerase chain reaction (PCR) test is required.[2],[3] In practice, the immunological test is cheaper and more widely used. Here, the authors tried to retrospectively analyze on the dengue immunoglobulin (Ig) test result among 115 patients with clinical diagnosis of dengue. Based on the analysis, the result is shown in [Table 1]. Based on this information, it can be seen that there are various patterns of Ig result among the cases with the clinical diagnosis of dengue. However, the acute illness (dengue IgM positive) can be completely confirmed in almost all cases. For the other cases with dengue IgM negative and dengue IgG positive (1.8%) indicated previous infection whereas the case with both dengue IgM and IgG negative might be on a window period. Based on the finding, it might seem that dengue diagnosis by clinical method is still applicable and can save the cost of immunological tests.
Table 1: Dengue Ig test result among 115 cases
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Conflicts of interest
There are no conflicts of interest.
References |
1. |
Wiwanitkit V. Dengue fever: Diagnosis and treatment. Expert Rev Anti Infect Ther 2010;8:841-5.
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2. |
Fatima A, Wang J. Review: Progress in the diagnosis of dengue virus infections and importance of point of care test: A review. Pak J Pharm Sci 2015;28:271-80.
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3. |
Guzmán MG, Vázquez S. Notes on the laboratory diagnosis of dengue virus. Rev Cubana Med Trop 2002;54:180-8.
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Source of Support: None, Conflict of Interest: None
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DOI: 10.4103/1755-6783.179111
Tables |
[Table 1]