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Table of Contents   
LETTER TO THE EDITOR  
Year : 2016  |  Volume : 9  |  Issue : 6  |  Page : 417-418
Rate of false positive IgM in cases of Zika virus infection: Thailand's situation


1 Sanitation 1 Medical Academic Center, Bangkok, Thailand
2 Faculty of Medicine, University of Nis, Nis, Serbia

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Date of Web Publication14-Nov-2016
 

How to cite this article:
Joob B, Wiwanitkit V. Rate of false positive IgM in cases of Zika virus infection: Thailand's situation. Ann Trop Med Public Health 2016;9:417-8

How to cite this URL:
Joob B, Wiwanitkit V. Rate of false positive IgM in cases of Zika virus infection: Thailand's situation. Ann Trop Med Public Health [serial online] 2016 [cited 2017 Mar 26];9:417-8. Available from: http://www.atmph.org/text.asp?2016/9/6/417/193953
Dear Sir,

Emerging Zika virus infection is the present problematic situation. Due to the confirmed problem in the pregnant, causing congenital microcephaly in offspring, the disease becomes the focused disease at present.[1],[2] The interesting situation is the dengue-like clinical feature. The problem in presently used dengue serological test for diagnosis and differentiation between the classical dengue and new Zika virus infection is noted.[1],[2] The false-positive dengue serological test can be seen in cases with Zika virus infection. Based on the previous available data on 7 confirmed cases of Zika virus in Thailand,[3] the false-positive IgM can be seen in 1 from 5 cases with data on dengue IgM test, giving the rate of 20%. This rate is considerably high. This means if we rely on dengue IgM test for the diagnosis of dengue, there can be 1 missed Zika virus infection diagnosis from 5 diagnosed dengue infections. This can be the explanation for why there are only a few reported cases of Zika virus infections despite it already circulates in many tropical countries.

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Conflicts of interest

There are no conflicts of interest.

 
   References Top

1.
Joob B, Wiwanitkit V. Zika virus infection and dengue: A new problem in diagnosis in a dengue-endemic area. Ann Trop Med Public Health 2015;8:145-6.  Back to cited text no. 1
  Medknow Journal  
2.
Wiwanitkit S, Wiwanitkit V. Acute viral hemorrhage disease: A summary on new viruses. J Acute Dis 2015;4:277-9.  Back to cited text no. 2
    
3.
Buathong R, Hermann L, Thaisomboonsuk B, Rutvisuttinunt W, Klungthong C, Chinnawirotpisan P, et al. Detection of Zika Virus Infection in Thailand, 2012-2014. Am J Trop Med Hyg 2015;93:380-3.  Back to cited text no. 3
    

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Correspondence Address:
Beuy Joob
Sanitation 1 Medical Academic Center, Bangkok
Thailand
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1755-6783.193953

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